Risk Factors for Early-onset Group B Streptococcal Sepsis: Estimation of Odds Ratios by Critical Literature Review

@article{Benitz1999RiskFF,
  title={Risk Factors for Early-onset Group B Streptococcal Sepsis: Estimation of Odds Ratios by Critical Literature Review},
  author={William E. Benitz and Jeffrey B. Gould and Maurice L. Druzin},
  journal={Pediatrics},
  year={1999},
  volume={103},
  pages={e77 - e77}
}
Objective. To identify and to establish the prevalence of ORs for factors associated with increased risk for early-onset group B streptococcal (EOGBS) infection in neonates. Study Design. Literature review and reanalysis of published data. Results. Risk factors for EOGBS infection include group B streptococcal (GBS)-positive vaginal culture at delivery (OR: 204), GBS-positive rectovaginal culture at 28 (OR: 9.64) or 36 weeks gestation (OR: 26.7), vaginal Strep B OIA test positive at delivery… 

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Risk Factors for Neonatal Sepsis
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TLDR
No strategy can prevent all EOGBS cases, but the attack rate can be reduced at a cost <$12 000 per prevented case, and Supplementing intrapartum prophylaxis with postpartum ampicillin in a few infants is more effective and less costly than providing intrapartsum proPHylaxis for more mothers.
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