Risk Factors for Cervical Human Papillomavirus Infection and High-Grade Intraepithelial Lesion in Women Aged 20 to 31 Years in Germany

@article{Remschmidt2013RiskFF,
  title={Risk Factors for Cervical Human Papillomavirus Infection and High-Grade Intraepithelial Lesion in Women Aged 20 to 31 Years in Germany},
  author={Cornelius Remschmidt and Andreas Martin Kaufmann and Ingke Hagemann and Elena Vartazarova and Ole Wichmann and Yvonne Deler{\'e}},
  journal={International Journal of Gynecologic Cancer},
  year={2013},
  volume={23},
  pages={519 - 526}
}
Background Persistent infection with high-risk human papillomaviruses (HPVs) can lead to cervical intraepithelial lesion and cervical cancer. Sexual behavior and smoking have been identified as risk factors for HPV infection. However, it is unclear which factors account for the persistence of HPV infection and for high-grade squamous intraepithelial lesions (HSIL). Therefore, we conducted a study to identify epidemiological risk factors for the following: (1) the presence of HPV among women… Expand
Prevalence of High-Risk Human Papillomavirus in Women with Normal and Abnormal Pap Smear: A Cross Sectional Study from a Tertiary Hospital in South India
Introduction Human Papillomavirus (HPV) has been identified as an important risk factor that predisposes to cervical cancer. Traditionally the Papanicolaou (Pap) smear test has been routinely usedExpand
Analysis of high risk HPV subtypes associated with cervical intraepithelial neoplasia: a single centre retrospective study in the Mediterranean region of Turkey.
TLDR
An HPV subtype study in this region is conducted by investigating the presence of cervical precancerous lesions in cases examined for high-risk HPV DNA with the PCR method in the cervicovaginal cytology materials and found to be positive. Expand
Prevalence and risk factors for cervical neoplasia: a cervical cancer screening program in Beijing
TLDR
The prevalence of cervical neoplasia is relatively high in Beijing, and women aged 46–55 years, those with a lower education level, those reporting bleeding after intercourse, and those affected by Trichomonas vaginalis infection, cervical inflammation and genital warts are at higher risk for HSIL. Expand
Cigarette Smoking Promotes Infection of Cervical Cells by High-Risk Human Papillomaviruses, but not Subsequent E7 Oncoprotein Expression
TLDR
To assess the effect of smoking on high-risk (hr) HPV DNA positivity and on the expression of HPV E7 oncoprotein, as a surrogate of persistent hrHPV infection, data are used from women recruited for the PIPAVIR project, which examined the role of E7 protein detection in cervical cancer screening. Expand
Factors Associated with Development of High-Grade Squamous Intraepithelial Lesions of the Uterine Cervix in Women Younger than 30 Years
TLDR
Early age at sexual debut, multiple sexual partners, history of genital warts and smoking are significant risk factors for developing HSIL in women younger than 30 years and cervical cancer screening should be considered in young women with such factors. Expand
Human papillomavirus genotype distribution and socio-behavioural characteristics in women with cervical pre-cancer and cancer at the start of a human papillomavirus vaccination programme: the CIN3+ plus study
TLDR
Introduction of the nonavalent vaccine could cover approximately 90% of CIN3+ lesions in Swiss women compared with around 60% with the quadrivalent vaccine. Expand
Human Papillomavirus prevalence and probable first effects of vaccination in 20 to 25 year-old women in Germany: a population-based cross-sectional study via home-based self-sampling
TLDR
A high prevalence of high-risk HPV genotypes in non-vaccinated women living in Germany that can be potentially prevented by vaccination is demonstrated and reinforces the recommendation to vaccinate girls in early adolescence. Expand
Mucosal and cutaneous Human Papillomavirus seroprevalence among adults in the prevaccine era in Germany - Results from a nationwide population-based survey.
TLDR
Prevalence of naturally acquired antibodies to HPV types which can be prevented by vaccination is high in both sexes and all age groups, and these data can serve as baseline estimates to evaluate the population-level impact of the current vaccination strategy. Expand
The impact of smoking on HPV infection and the development of anogenital warts
TLDR
Most current data demonstrate an association between smoking, increased anogenitals HPV infection, and development of anogenital warts, and these data add to the long list of reasons for making smoking cessation a keystone of patient health. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 39 REFERENCES
The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice.
TLDR
HPV screening that distinguishes HPV16 and HPV18 from other oncogenic HPV types may identify women at the greatest risk of > or = CIN3 and may permit less aggressive management of other women with onCogenic HPV infections. Expand
Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study
TLDR
The findings suggest that attempts to exploit the association between cervical neoplasia and HPV infection to improve effectiveness of cervical screening programmes might be undermined by the limited inferences that can be drawn from the characterisation of a woman's HPV status at a single point in time, and the short lead time gained by its detection. Expand
Prevalence of low‐risk and high‐risk types of human papillomavirus and other risk factors for HPV infection in Germany within different age groups in women up to 30 years of age: An epidemiological observational study
TLDR
This epidemiological study shows that high‐risk HPV infection is common in young women in Germany and vaccination of young women could have a potential impact on the prevention of HPV infection and cervical disease. Expand
The absolute risk of cervical abnormalities in high-risk human papillomavirus-positive, cytologically normal women over a 10-year period.
TLDR
The results indicate that even a single positive HPV test in cytologically negative women is substantially predictive of high-grade CIN and suggest that HC2 testing can help stratify women into different risk categories. Expand
A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion.
TLDR
Although virtually all HPV infections clear within 2 years, the remaining infections have a high potential for persistence and, by implication, progression to precancer and cancer. Expand
Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: A longitudinal French cohort study
TLDR
The incidence of cytologic abnormalities strongly depended on baseline viral load and HR‐HPV persistence and maintenance of cytological abnormalities was associated with the outcome of HR‐ HPV status. Expand
Sexual behaviour and smoking as determinants of cervical HPV infection and of CIN3 among those infected: a case–control study nested within the Manchester cohort
TLDR
A three-arm case-control study nested within a large population-based cohort of women screened for HPV at entry using L1 consensus primer PCR found a striking division between risk factors for infection and those predictive of disease. Expand
Human papillomavirus infection and time to progression and regression of cervical intraepithelial neoplasia.
TLDR
Preursor lesions of the cervix persist longer and progress more quickly in women with oncogenic HPV infections than in womenwith non-oncogenic infections or without HPV, which may help identify those that are likely to progress rapidly. Expand
Human Papillomavirus and Cervical Cancer
  • E. Burd
  • Medicine
  • Clinical Microbiology Reviews
  • 2003
TLDR
Currently, the clearest role for HPV DNA testing is to improve diagnostic accuracy and limit unnecessary colposcopy in patients with borderline or mildly abnormal cytologic test results. Expand
Human papillomavirus type distribution in invasive cervical cancer and high‐grade cervical lesions: A meta‐analysis update
TLDR
A meta‐analyses of HPV type distribution in invasive cervical cancer (ICC) and high‐grade squamous intraepithelial lesions (HSIL) identified a total of 14,595 and 7,094 cases, respectively, suggesting differences in type‐specific risks for progression. Expand
...
1
2
3
4
...