Risk Factors and Pooled Rate of Prolonged Opioid Use Following Trauma or Surgery: A Systematic Review and Meta-(Regression) Analysis

  title={Risk Factors and Pooled Rate of Prolonged Opioid Use Following Trauma or Surgery: A Systematic Review and Meta-(Regression) Analysis},
  author={Amin Mohamadi and Jimmy J. Chan and Jayson Lian and Casey L. Wright and Arden M Marin and Edward K. Rodriguez and Arvind G. von Keudell and Ara Nazarian},
  journal={The Journal of Bone and Joint Surgery},
Background: Prolonged use of opioids initiated for surgical or trauma-related pain management has become a global problem. While several factors have been reported to increase the risk of prolonged opioid use, there is considerable inconsistency regarding their significance or effect size. Therefore, we aimed to pool the effects of risk factors for prolonged opioid use following trauma or surgery and to assess the rate and temporal trend of prolonged opioid use in different settings. Methods… 

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