Rising antigenemia levels may be misleading in pre-emptive therapy of human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.

@article{Gerna2005RisingAL,
  title={Rising antigenemia levels may be misleading in pre-emptive therapy of human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.},
  author={Giuseppe Gerna and Daniele Lilleri and Marco Zecca and Emilio Paolo Alessandrino and Fausto Baldanti and Maria Grazia Revello and Franco Locatelli},
  journal={Haematologica},
  year={2005},
  volume={90 4},
  pages={
          526-33
        }
}
BACKGROUND AND OBJECTIVES Hematopoietic stem cell transplant (HSCT) recipients after show rising levels of antigenemia during pre-emptive ganciclovir treatment of human cytomegalovirus (HCMV) infection. This raises some doubts about the therapeutic decisions to be taken. DESIGN AND METHODS Three groups of HSCT recipients with HCMV infection undergoing anti-viral treatment were identified: group A, showing increasing antigenemia and decreasing viremia and DNAemia; group B, with simultaneous… CONTINUE READING

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