Risedronate treatment does not increase microdamage in the canine femoral neck.

  title={Risedronate treatment does not increase microdamage in the canine femoral neck.},
  author={M. Forwood and D. Burr and Y. Takano and D. Eastman and P. N. Smith and J. Schwardt},
  volume={16 6},
  • M. Forwood, D. Burr, +3 authors J. Schwardt
  • Published 1995
  • Medicine
  • Bone
  • Cortical and trabecular bone from the femoral neck of 24 adult female beagle dogs was examined for microdamage following 2 years of treatment with risedronate (NE-58095). Specimens of the femoral neck, sectioned between the femoral head and the intertrochanteric groove, were bulk stained in 1% basic fuchsin in graded alcohols and embedded in methylmethacrylate. Five transverse sections of 100 microns from each specimen were examined for microdamage and measurement of cortical and trabecular… CONTINUE READING
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