Rise and fall of the delta globin gene.

  title={Rise and fall of the delta globin gene.},
  author={Sandra L Martin and Karen A. Vincent and A. C. Wilson},
  journal={Journal of molecular biology},
  volume={164 4},
This paper examines the molecular basis for the origin and subsequent silencing of the delta globin gene during the evolution of higher primates. We cloned and sequenced the delta gene from representatives of the two most distantly related types of Old World monkeys in which the gene is silent. The silent delta genes of these two monkeys (rhesus and colobus) are highly homologous to each other (97.5%) and to the functional human delta gene (94%). The presumed mutation that silenced the delta… CONTINUE READING
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