RirA is the iron response regulator of the rhizobactin 1021 biosynthesis and transport genes in Sinorhizobium meliloti 2011.

@article{Viguier2005RirAIT,
  title={RirA is the iron response regulator of the rhizobactin 1021 biosynthesis and transport genes in Sinorhizobium meliloti 2011.},
  author={Caroline Viguier and P{\'a}raic {\'O} Cu{\'i}v and Paul Clarke and Michael J. O'Connell},
  journal={FEMS microbiology letters},
  year={2005},
  volume={246 2},
  pages={235-42}
}
The genes encoding the biosynthesis and transport of rhizobactin 1021, a siderophore produced by Sinorhizobium meliloti, are negatively regulated by iron. Mutagenesis of rirA, the rhizobial iron regulator, resulted in abolition of the iron responsive regulation of the biosynthesis and transport genes. Bioassay analysis revealed that the siderophore is produced in the presence of iron in a rirA mutant. RNA analysis and GFP fusions supported the conclusion that RirA is the mediator of iron… CONTINUE READING
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