Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity.

@article{Uldbjerg1983RipeningOT,
  title={Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity.},
  author={Niels Uldbjerg and Gunvor Ekman and Anders Malmstr{\"o}m and Kerstin Olsson and Ulf Ulmsten},
  journal={American journal of obstetrics and gynecology},
  year={1983},
  volume={147 6},
  pages={662-6}
}
Connective tissue in biopsy specimens taken from the lower part of the uterine cervix in 40 pregnant women at various gestational ages was compared to that in similar biopsy specimens from 15 nonpregnant women. The concentrations of collagen, sulfated glycosaminoglycans, and hyaluronic acid decreased during pregnancy. At the gestational age of 10 weeks, the collagen concentration was 70%, and at term 30%, of that in the nonpregnant cervix. After delivery, no further decrease was observed. The… CONTINUE READING

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