Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts

  title={Ringo – an R/Bioconductor package for analyzing ChIP-chip readouts},
  author={Joern Toedling and Oleg Sklyar and Tammo Krueger and Jenny J. Fischer and Silke Sperling and Wolfgang Huber},
  journal={BMC Bioinformatics},
  pages={221 - 221}
Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modifications. However, the raw microarray intensity readings themselves are not immediately useful to researchers, but require a number of bioinformatic analysis steps. Identified enriched regions need to be bioinformatically annotated and compared to related datasets by statistical methods. We present a free, open-source R package… CONTINUE READING
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