"Ring-fencing" BRCA1 tumor suppressor activity.


BRCA1 is a crucial human breast and ovarian cancer tumor suppressor gene. The article by Drost et al. in this issue of Cancer Cell together with a recent paper in Science now provide a clearer picture of how this large and complex protein suppresses tumorigenesis.

DOI: 10.1016/j.ccr.2011.11.019

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@article{Patel2011RingfencingBT, title={"Ring-fencing" BRCA1 tumor suppressor activity.}, author={Ketan J Patel and Gerry P Crossan and Michael R. G. Hodskinson}, journal={Cancer cell}, year={2011}, volume={20 6}, pages={693-5} }