Ring chromosome 8 and trisomy 8 in a patient with acute myeloid leukemia

@article{Kar2009RingC8,
  title={Ring chromosome 8 and trisomy 8 in a patient with acute myeloid leukemia},
  author={Bibhas Kar and B. Nandhini and R. Revathi},
  journal={Indian Journal of Hematology and Blood Transfusion},
  year={2009},
  volume={25},
  pages={30-32}
}
We describe a child with Acute Myeloid Leukemia (AML M7) with trisomy 8 and ring chromosome 8. Ring chromosome 8 associated with AML is uncommon and is reported to have a poor outcome. The combination of trisomy 8 and ring chromosome 8 has not been previously reported. This 15-month-old girl had presented with a history of fever, weight loss of 1 kg, gum bleeds and pallor. Clinical examinations revealed no nodes or organomegaly. Investigations revealed pancytopenia and elevated serum LDH. Bone… Expand
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