Riluzole , a Novel Antiglutamate , Prevents Memory Loss Hippocampal Neuronal Damage in lschemic Gerbils and

@inproceedings{Malgouris2003RiluzoleA,
  title={Riluzole , a Novel Antiglutamate , Prevents Memory Loss Hippocampal Neuronal Damage in lschemic Gerbils and},
  author={Christiane Malgouris and Florence Bardot and ’ Marc Daniel and Fabienne Pellis and Jean Rataud and Andr{\'e} Uzan and J. -C. Blanchard and Pierre M. Laduron},
  year={2003}
}
The neuroprotective effects of riluzole, a novel antiglutamate, has been demonstrated in a model of ischemia induced in female Mongolian gerbils by transient bilateral carotid occlusion. Riluzole was administered at a dose of 4 mg/kg, i.p., just before, 4 hr after, and for the 14 d following the transient bilateral carotid occlusion (10 min). The functional sequelae of ischemic damage were assessed using a memory test (passive avoidance) and the extent of neuronal damage by histological… CONTINUE READING
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