Right heart failure chronically stimulates heat shock protein 72 in heart and liver but not in other tissues.

@article{Comini1996RightHF,
  title={Right heart failure chronically stimulates heat shock protein 72 in heart and liver but not in other tissues.},
  author={L Sabbatini Comini and Giuseppina Gaia and Salvatore Curello and Claudio Ceconi and Evasio Pasini and M. Kathryn Di Benigno and Tiziana Bachetti and Roberto B. Ferrari},
  journal={Cardiovascular research},
  year={1996},
  volume={31 6},
  pages={
          882-90
        }
}
OBJECTIVES During cardiac failure several ontogenically developed adaptional mechanisms are activated. Among these, heat-shock proteins (HSP) are expressed in response to stress. The aim of the present study was to investigate the HSP72 protein expression in lungs, liver, cardiac and skeletal muscles during congestive heart failure (CHF). METHODS CHF was induced in Sprague-Dawley rats by a single intraperitoneal injection of monocrotaline (50 mg/kg). Two groups of animals emerged: a CHF group… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Effects of aging on the cardiac remodeling induced by chronic high-altitude hypoxia in rat.

  • American journal of physiology. Heart and circulatory physiology
  • 2004
VIEW 3 EXCERPTS
CITES BACKGROUND & RESULTS

Changes in skeletal muscle heat shock proteins: pathological significance.

  • Frontiers in bioscience : a journal and virtual library
  • 2001
VIEW 1 EXCERPT
CITES BACKGROUND

Hypothesis to explain poor outcomes in the ALLHAT and V-HeFT trials: decreased expression of heat shock proteins

  • Current controlled trials in cardiovascular medicine
  • 2001
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the BZadrenoceptor

S Minatoguchi, H Majewski
  • Nature
  • 1995

Hyper - tension , aging , and myocardial synthesis of heatshock protein 72

MM Bradford
  • Hypertension
  • 1994

Plasma norepinephrine, plasma renin activity, and congestive heart failure. Relations to survival and the effects of therapy in the V-HeFT II. Circulation 1993;87(Suppl

TS Rector, S Goldman, A. Simon
  • 1993