Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report.

@article{Brugada1992RightBB,
  title={Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report.},
  author={Pedro Brugada and Josep Brugada},
  journal={Journal of the American College of Cardiology},
  year={1992},
  volume={20 6},
  pages={
          1391-6
        }
}
  • P. Brugada, J. Brugada
  • Published 15 November 1992
  • Medicine
  • Journal of the American College of Cardiology
Two cases of sudden cardiac death syndrome associated with right bundle branch block and ST segment elevation
In 1992, Brugada described clinical features of patients with aborted sudden cardiac death who showed no demonstrable heart disease and a peculiar ECG pattern consisting of right bundle branch block
Clinical and Genetic Heterogeneity of Right Bundle Branch Block and ST-Segment Elevation Syndrome: A Prospective Evaluation of 52 Families
TLDR
At variance with current views, asymptomatic patients are at lower risk for sudden death and programmed electrical stimulation identifies only a fraction of individuals at risk, and sodium channel blockade fails to unmask most silent gene carriers.
Further Characterization of the Syndrome of Right Bundle Branch Block, ST Segment Elevation, and Sudden Cardiac Death
TLDR
Long‐term follow‐up of survivors failed to show progression to any form of right or left ventricular cardiomyopatby, especially those related to asymptomatic and intermittent forms.
The Syndrome of Right Bundle Branch Block, ST Segment Elevation in V1 to V3 and Sudden Death. Are Asymptomatic Patients at High Risk for Sudden Death?
TLDR
The question of whether the presence of an abnormal ECG without symptoms indicates that the patient is affected by the disease and what the prognosis is is raised.
Right bundle-branch block and ST-segment elevation in leads V1 through V3: a marker for sudden death in patients without demonstrable structural heart disease.
TLDR
Patients without demonstrable structural heart disease and an ECG pattern of right bundle-branch block and ST-segment elevation in leads V1 through V3 are at risk for sudden death and an implantable defibrillator seems to be the present treatment of choice.
Ventricular Tachycardia or Conduction Disease: What Is the Mechanism of Death in Brugada Syndrome?
TLDR
The hypothesis that “marked dispersion refractoriness of cardiac tissue or extreme anisotropic conduction properties of the conduction system and the venticular muscle” was the underlying photophysiologic substrate of the syndrome was advanced.
“Brugada Syndrome”: A Structural Cardiomyopathy or a Functional Electrical Disease?
TLDR
This syndrome is associated to a high recurrence of ventricular fibrillation in patients who have already suffered from one or multiple episodes of aborted sudden death and asymptomatic persons with this electrocardiographic pattern are also at high risk of sudden death.
Right Bundle-Branch Block and ST-Segment Elevation in Leads V 1 Through V 3 A Marker for Sudden Death in Patients Without Demonstrable Structural Heart Disease
TLDR
Patients without demonstrable structural heart disease and an ECG pattern of right bundle-branch block and ST-segment elevation in leads V1 through V3 are at risk for sudden death.
Right Bundle Branch Block, Right Precordial ST-Segment Elevation, and Sudden Death in Young People
TLDR
Right precordial ST-segment elevation was found in 14% of young sudden death victims with available ECG, characterized a subgroup of patients who share with Brugada patients the propensity to die from non–exercise-related cardiac arrest and to exhibit dynamic ECG changes and polymorphic ventricular tachycardia.
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