Rifaximin for the Treatment of Hepatic Encephalopathy

@article{Lawrence2008RifaximinFT,
  title={Rifaximin for the Treatment of Hepatic Encephalopathy},
  author={Kenneth Lawrence and J. Klee},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2008},
  volume={28}
}
  • K. Lawrence, J. Klee
  • Published 1 August 2008
  • Medicine, Psychology
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Objective. To review the effectiveness and safety of rifaximin for the treatment of hepatic encephalopathy. 
RIFAXAMIN VS LACTULOSE; IN IMPROVING CIRRHOTIC PATIENTS WITH HEPATIC ENCEPHALOPATHY
TLDR
Rifaxamin and Lactulose are compared in improving the grades of hepatic encephalopathy in patients with decompensated liver disease to compare their use in a Randomized controlled trial.
Effects of rifaximin versus nonabsorbable disaccharides in hepatic encephalopathy
Lactulose is recommended as secondary prophylaxis after the initial episode and rifaximin as an add‐on to lactulose for preventing recurrent episodes of hepatic encephalopathy (HE) after the second
Rifaximin for the treatment of hepatic encephalopathy
TLDR
Rifaximin is safe and well-tolerated for the treatment of minimal and overt HE and for the maintenance of HE remission.
Current and emerging strategies for treating hepatic encephalopathy.
Rifaximina para encefalopatía hepática en niños: Caso clínico
SUMMARY Rifaximin is an antibiotic recently approved for the treatment of hepatic encephalopathy in adults. In children more than 12 year-old, it has been approved for travelers’ diarrhea and it is
Gut instinct: Rifaximin for the prevention of hepatic encephalopathy
TLDR
Over a 6-month period, treatment with rifaximin maintained remission from hepatic encephalopathy more effectively than did placebo, and also significantly reduced the risk of hospitalization involving hepaticEncephalopathy.
Rifaximin treatment in hepatic encephalopathy.
TLDR
Over a 6-month period, treatment with rifaximin maintained remission from hepatic encephalopathy more effectively than did placebo, and also significantly reduced the risk of hospitalization involving hepaticEncephalopathy.
Rifaximin therapy and hepatic encephalopathy: Pros and cons.
Hepatic encephalopathy (HE) is the second most common major complication in cirrhotics and it significantly impacts quality of life. Therapeutic approaches for HE treatment and prevention mainly
Rifaximin for the treatment of hepatic encephalopathy.
FUNCTIONAL INTESTINAL DISORDERS AND ITS ASSOCIATION WITH MICROFLORA DISORDERS IN CIRRHOTIC PATIENTS WIH PORTAL HYPERTENSIVE COLOPATHY
TLDR
The study found that use of rifaximin followed by a treatment with bifiform may be useful to normalize gut microflora and eliminate dyspeptic disorders in cirrhotic patients wih portal hypertensive colopathy.
...
1
2
3
4
...

References

SHOWING 1-10 OF 35 REFERENCES
Rifaximin in the treatment of chronic hepatic encephalopathy.
Treatment of hepatic encephalopathy with L/105, a new non-absorbable rifamycin
Experimentation sur un nouveau derive de la rifamycine, le L/105: son efficacite contre les bacteries aerobiques et anaerobiques est demontree dans une analyse in vitro. D'autre part, un essai
A non-absorbable rifamycin for treatment of hepatic encephalopathy.
TLDR
The short-term efficacy of a non-absorbable rifamycin, rifaximin, was studied in comparison with paramomycin in 20 cirrhotic patients with high levels of NH3 and impaired number connection test (NCT).
Comparison of Rifaximin and Lactulose for the Treatment of Hepatic Encephalopathy: A Prospective Randomized Study
TLDR
Rifaximin proved to be as safe and as effective as lactulose for the treatment of Korean patients with hepatic encephalopathy, and the posttreatment levels of these measures were similar for the rifaximine-treated groups, as was the HE index.
Rifaximin, a non-absorbable rifamycin, for the treatment of hepatic encephalopathy. A double-blind, randomised trial.
TLDR
The usefulness of rifaximin in the treatment of HE is confirmed, supporting its use as a first-choice antibiotic, particularly in patients intolerant to neomycin or with impaired renal function.
Analysis of hospitalizations comparing rifaximin versus lactulose in the management of hepatic encephalopathy.
Rifaximin versus neomycin on hyperammoniemia in chronic portal systemic encephalopathy of cirrhotics. A double-blind, randomized trial.
TLDR
Rifaximin is at least as effective as neomycin in the achievement and maintenance of low blood ammonia levels in cirrhotics with chronic PSE.
Rifaximin: a novel nonabsorbed rifamycin for gastrointestinal disorders.
  • J. Adachi, H. Dupont
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2006
TLDR
Rifaximin has been demonstrated to reduce the duration of traveler's diarrhea secondary to noninvasive bacterial pathogens and recently has been shown to reduceThe occurrence of the disease when used for chemoprophylaxis.
...
1
2
3
4
...