Rifampicin-induced elevation of serum bile acids in man

@article{Galeazzi1980RifampicininducedEO,
  title={Rifampicin-induced elevation of serum bile acids in man},
  author={D R Galeazzi and Ivano Lorenzini and Francesco Orlandi},
  journal={Digestive Diseases and Sciences},
  year={1980},
  volume={25},
  pages={108-112}
}
Fasting and postprandial serum bile acid concentrations were determined by gas-liquid chromatography in 20 consecutive individuals (14 normal subjects, 6 cirrhotics) before and after administration of rifampicin in a single dose of 900 mg, using each individual as his own control. In the normal subjects the 2-hr postprandial level was 2.9±0.2 μM (mean±1sem) prior to drug administration. Following rifampicin, it was 7.7±0.5 μM (P<0.0005). In the patients with liver cirrhosis the 2-hr… CONTINUE READING

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