Rifampicin attenuates brain damage in focal ischemia.

  title={Rifampicin attenuates brain damage in focal ischemia.},
  author={Burak Yulug and Ulkan Kilic and Ertugrul Kilic and Mathias B{\"a}hr},
  journal={Brain research},
  volume={996 1},
Rifampicin is an antibacterial agent that is widely used in tuberculosis and leprosy therapy. Interestingly, some experimental studies indicate that rifampicin acts as a hydroxyl radical scavenger and a glucocorticoid receptor activator. In this study, the neuroprotective effect of rifampicin was evaluated after transient and permanent focal cerebral ischemia. Anaesthetized male C57BL/6j mice were submitted to permanent or transient thread occlusion of the middle cerebral artery (MCA… CONTINUE READING
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