Rickettsia conorii Transcriptional Response within Inoculation Eschar

@article{Renesto2008RickettsiaCT,
  title={Rickettsia conorii Transcriptional Response within Inoculation Eschar},
  author={Patricia Renesto and Clarisse Rovery and Jacques Schrenzel and Quentin Leroy and Antoine Huyghe and Wen-Jun Li and Hubert L{\'e}pidi and Patrice François and Didier Raoult},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={694 - 719}
}
BACKGROUND Rickettsia conorii, the causative agent of the Mediterranean spotted fever, is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within infected skin is critical for our understanding of rickettsiosis. METHODOLOGY/PRINCIPAL FINDINGS Here, we report the first genome-wide analysis of R. conorii… CONTINUE READING

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