Richter syndrome and brain involvement: low-grade lymphoma relapsing as cerebral high-grade lymphoma.

@article{Stuplich2012RichterSA,
  title={Richter syndrome and brain involvement: low-grade lymphoma relapsing as cerebral high-grade lymphoma.},
  author={Moritz Stuplich and Karin Tina Mayer and Young Zoo Kim and Sharmilan Thanendrarajan and Matthias Simon and Niklas Schaefer and Martin Glas and Ingo G. H. Schmidt-Wolf and Ulrich Herrlinger},
  journal={Acta haematologica},
  year={2012},
  volume={127 2},
  pages={93-5}
}
Richter syndrome (RS) describes the development of high-grade non-Hodgkin's lymphoma (NHL) from low-grade NHL. RS isolated to the brain is very rare and has a poor prognosis. We describe the cases of high-grade large B-cell diffuse NHL in a 56-year-old male with chronic lymphocytic leukemia and in a 71-year-old female with previously unknown low-grade NHL… CONTINUE READING