Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.

  title={Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling.},
  author={Joy Xin Wang and Elaine R. Lee and Dianali Rivera Morales and Jinsoo Lim and Ronald R. Breaker},
  journal={Molecular cell},
  volume={29 6},
We have identified a highly conserved RNA motif that occurs upstream of genes involved in S-adenosyl-L-methionine (SAM) recycling in many Gram-positive and Gram-negative species of bacteria. The phylogenetic distribution and the conserved structural features of representatives of this motif are indicative of riboswitch function. Riboswitches are widespread metabolite-sensing gene control elements that are typically found in the 5' untranslated regions (UTRs) of bacterial mRNAs. We… CONTINUE READING
34 Citations
67 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 34 extracted citations


Publications referenced by this paper.
Showing 1-10 of 67 references

A Short Course in Bacterial Genetics 72 (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press)

  • J. H. Miller
  • 1992
Highly Influential
2 Excerpts

Escherichia coli

  • F. Della Ragione, M. Porcelli, M. Carteni-Farina, V. Zappia, A. E. Pegg
  • 1985
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…