Ribosome fidelity: tRNA discrimination, proofreading and induced fit.

@article{Rodnina2001RibosomeFT,
  title={Ribosome fidelity: tRNA discrimination, proofreading and induced fit.},
  author={Marina V. Rodnina and Wolfgang Wintermeyer},
  journal={Trends in biochemical sciences},
  year={2001},
  volume={26 2},
  pages={124-30}
}
The ribosome selects aminoacyl-tRNAs with high fidelity. Kinetic studies reveal that codon-anticodon recognition both stabilizes aminoacyl-tRNA binding on the ribosome and accelerates reactions of the productive pathway, indicating an important contribution of induced fit to substrate selection. Similar mechanisms are used by other template-programmed enzymes, such as DNA and RNA polymerases. 

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