Ribosome binding to mitochondria is regulated by GTP and the transit peptide.

@article{Crowley1998RibosomeBT,
  title={Ribosome binding to mitochondria is regulated by GTP and the transit peptide.},
  author={Kathleen S. Crowley and Ronald M Payne},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 27},
  pages={
          17278-85
        }
}
The association between ribosomes and the pore proteins at the endoplasmic reticulum membrane is important to co-translational translocation. To determine if a similar association occurs between the ribosome and mitochondrial membrane protein(s) during protein import in higher eukaryotes, we examined ribosome-mitochondria binding. By using spectral measurements, analysis of mitochondrial associated RNA, and electron microscopy, we demonstrated that ribosomes stably bind to purified rat liver… CONTINUE READING
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Import of nuclear-encoded mitochondrial proteins: a cotranslational perspective.

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