Ribonucleases from rat and bovine liver: purification, specificity and structural characterization.

@article{Zhao1998RibonucleasesFR,
  title={Ribonucleases from rat and bovine liver: purification, specificity and structural characterization.},
  author={Wei Zhao and Zsofia Kote-Jarai and Y van Santen and Jan Hofsteenge and Jaap J. Beintema},
  journal={Biochimica et biophysica acta},
  year={1998},
  volume={1384 1},
  pages={55-65}
}
The presence of four members of the pyrimidine-specific ribonuclease superfamily was demonstrated in rat liver. Three of them (RL1, RL2 and RL3) were purified and showed ribonuclease activity at pH 7.5 with yeast RNA as substrate. RL1 is identical to rat pancreatic ribonuclease (ribonuclease 1). N-terminal sequence analysis showed the presence of the native… CONTINUE READING