Ribonuclease and its inhibitor in red blood cells in CF.

Abstract

A disturbed activity of ribonuclease (RNAase) and its natural inhibitor was found in cystic fibrosis patients (CF); Heterozygotes had normal RNAase but increased inhibitor activities; both groups compared with age-matched controls. RNAase is involved in the breakdown of RNA. In the cell it is bound to an inhibitor and thus inactive (Bardoń 1976… (More)

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