Ribonuclease H from rat liver. II. Partial purification and characterization of cytosol ribonuclease H1.

Abstract

We have detected in rat liver cytosol three enzymes (termed C-1, C-2, and C-3) which cleaved the RNA moiety of RNA-DNA hybrid. These enzymes were separated from each other by DEAE-Sephadex and Sephadex G-200 chromatography. C-1 and C-2 specifically act on the RNA moiety of RNA-DNA hybrid, while C-3 degrades single-stranded RNA as well as the RNA of the… (More)

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@article{Tashiro1978RibonucleaseHF, title={Ribonuclease H from rat liver. II. Partial purification and characterization of cytosol ribonuclease H1.}, author={Fumihito Tashiro and Yuko Ueno}, journal={Journal of biochemistry}, year={1978}, volume={84 2}, pages={395-402} }