• Corpus ID: 14078807

Riboflavin and cancer: a review.

@article{Rivlin1973RiboflavinAC,
  title={Riboflavin and cancer: a review.},
  author={Richard S. Rivlin},
  journal={Cancer research},
  year={1973},
  volume={33 9},
  pages={
          1977-86
        }
}
  • R. Rivlin
  • Published 1 September 1973
  • Biology, Medicine
  • Cancer research
Summary The relationship of riboflavin to cancer is intriguing but many gaps remain in our knowledge. Several studies indicate that riboflavin deficiency inhibits tumor growth in experimental animals and possibly in man, but the precise mechanisms involved have not been elucidated. Azo dye carcinogenesis in liver appears to be a special case in that riboflavin deficiency increases the potency of these drugs in tumor causation, probably in large measure because flavin cofactors are involved in… 

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Findings indicate that combination of cisplatin with riboflavin under photo illumination synergizes its anti cancer activity towards cancer cells and attenuates the cisPlatin induced toxicities.

Lumichrome Inhibits Human Lung Cancer Cell Growth and Induces Apoptosis via a p53-Dependent Mechanism

It is shown for the first time that unlike riboflavin, lumichrome can suppress lung cancer cell growth and reduce survival in both normal and anchorage-independent conditions.

Riboflavin: The Health Benefits of a Forgotten Natural Vitamin

It is appropriate to consider a re-evaluation of the importance of RF in terms of its beneficial properties following the latest findings about the link between RF and different clinical aberrations.

Disturbances in the formation of FAD and covalently bound flavins in Novikoff hepatoma from riboflavin-deficient rats.

The hypothesis that in conditions of rib oflavin deprivation, Novikoff hepatoma maintains the levels of the physiologically important flavin coenzymes at the expense of the free riboflavin fraction is supported.

Some interactions of light, riboflavin, and aflatoxin B1 in vivo and in vitro.

Low, carcinogenic doses of aflatoxin may complex with endogenous, photosensitized riboflavin, inhibiting its degradation into carcinogenic metabolites, and this interpretation gains support from studies in vitro that showed that rib oflavin quenched a flatoxin photodegradation, perhaps by complexing with aflat toxin.
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