Riboflavin analogs and inhibitors of riboflavin biosynthesis

@article{Mack2006RiboflavinAA,
  title={Riboflavin analogs and inhibitors of riboflavin biosynthesis},
  author={Matthias Mack and Simon Grill},
  journal={Applied Microbiology and Biotechnology},
  year={2006},
  volume={71},
  pages={265-275}
}
  • M. MackS. Grill
  • Published 11 April 2006
  • Biology, Chemistry
  • Applied Microbiology and Biotechnology
Flavins are active components of many enzymes. In most cases, riboflavin (vitamin B2) as a coenzyme represents the catalytic part of the holoenzyme. Riboflavin is an amphiphatic molecule and allows a large variety of different interactions with the enzyme itself and also with the substrate. A great number of active riboflavin analogs can readily be synthesized by chemical methods and, thus, a large number of possible inhibitors for many different enzyme targets is conceivable. As mammalian and… 

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