Riboflavin analogs and inhibitors of riboflavin biosynthesis

  title={Riboflavin analogs and inhibitors of riboflavin biosynthesis},
  author={M. Mack and S. Grill},
  journal={Applied Microbiology and Biotechnology},
  • M. Mack, S. Grill
  • Published 2006
  • Medicine, Chemistry
  • Applied Microbiology and Biotechnology
  • Flavins are active components of many enzymes. In most cases, riboflavin (vitamin B2) as a coenzyme represents the catalytic part of the holoenzyme. Riboflavin is an amphiphatic molecule and allows a large variety of different interactions with the enzyme itself and also with the substrate. A great number of active riboflavin analogs can readily be synthesized by chemical methods and, thus, a large number of possible inhibitors for many different enzyme targets is conceivable. As mammalian and… CONTINUE READING
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