Ribifolin, an orbitide from Jatropha ribifolia, and its potential antimalarial activity.


A new orbitide named ribifolin was isolated and characterized from Jatropha ribifolia using mass spectrometry, NMR spectroscopy, quantitative amino acid analysis, molecular dynamics/simulated annealing, and Raman optical activity measurements and calculations. Ribifolin (1) and its linear form (1a) were synthesized by solid-phase peptide synthesis, followed… (More)
DOI: 10.1021/np5007668


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