Rhythmic bursting in the pre-Bötzinger complex: mechanisms and models.

Ilya A. Rybak, Yaroslav I. Molkov, Patrick E. Jasinski, Natalia Shevtsova, Jeffrey C. Smith
Published 2014 in Progress in brain research

Abstract

The pre-Bötzinger complex (pre-BötC), a neural structure involved in respiratory rhythm generation, can generate rhythmic bursting activity in vitro that persists after blockade of synaptic inhibition. Experimental studies have identified two mechanisms potentially involved in this activity: one based on the persistent sodium current (INaP) and the other… (More)

DOI: 10.1016/B978-0-444-63274-6.00001-1

Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

Ryland W Pace, Devin D Mackay, Jack L Feldman, Christopher A Del Negro
The Journal of physiology
2007

Rhythmic bursting in the pre-Bötzinger complex: mechanisms and models.

Abstract

Topics

6 Figures and Tables

Cited By

Substitution of extracellular Ca2+ by Sr2+ prolongs inspiratory burst in pre-Bötzinger complex inspiratory neurons.

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits

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References

Outward Currents Contributing to Inspiratory Burst Termination in preBötzinger Complex Neurons of Neonatal Mice Studied in Vitro

Differential Contribution of Pacemaker Properties to the Generation of Respiratory Rhythms during Normoxia and Hypoxia

Two types of independent bursting mechanisms in inspiratory neurons: an integrative model

Asymmetric control of inspiratory and expiratory phases by excitability in the respiratory network of neonatal mice in vitro.

Calcium-activated nonspecific cation current and synaptic depression promote network-dependent burst oscillations.

Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation.

Respiratory Rhythm An Emergent Network Property?

Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons.

Models of respiratory rhythm generation in the pre-Bötzinger complex. II. Populations Of coupled pacemaker neurons.

Slides referencing similar topics

Rhythmic bursting in the pre-Bötzinger complex: mechanisms and models.

Abstract

Topics

6 Figures and Tables

Cited By

Substitution of extracellular Ca2+ by Sr2+ prolongs inspiratory burst in pre-Bötzinger complex inspiratory neurons.

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits

Understanding the Generation of Network Bursts by Adaptive Oscillatory Neurons

Timescales and Mechanisms of Sigh-Like Bursting and Spiking in Models of Rhythmic Respiratory Neurons

Central Pattern Generators: Mechanisms of Operation and Their Role in Controlling Automatic Movements

Mixed-mode oscillations and population bursting in the pre-Bötzinger complex.

Organization of the Mammalian Locomotor CPG: Review of Computational Model and Circuit Architectures Based on Genetically Identified Spinal Interneurons

Voltage-Dependent Rhythmogenic Property of Respiratory Pre-Bötzinger Complex Glutamatergic, Dbx1-Derived, and Somatostatin-Expressing Neuron Populations Revealed by Graded Optogenetic Inhibition.

Voltage-Dependent Rhythmogenic Property of Respiratory Pre-Bötzinger Complex Glutamatergic, Dbx1-Derived, and Somatostatin-Expressing Neuron Populations Revealed by Graded Optogenetic Inhibition123

Organization of left-right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling.

References

Outward Currents Contributing to Inspiratory Burst Termination in preBötzinger Complex Neurons of Neonatal Mice Studied in Vitro

Differential Contribution of Pacemaker Properties to the Generation of Respiratory Rhythms during Normoxia and Hypoxia

Two types of independent bursting mechanisms in inspiratory neurons: an integrative model

Asymmetric control of inspiratory and expiratory phases by excitability in the respiratory network of neonatal mice in vitro.

Calcium-activated nonspecific cation current and synaptic depression promote network-dependent burst oscillations.

Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

Sodium and calcium current-mediated pacemaker neurons and respiratory rhythm generation.

Respiratory Rhythm An Emergent Network Property?

Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons.

Models of respiratory rhythm generation in the pre-Bötzinger complex. II. Populations Of coupled pacemaker neurons.

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