Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABA(A)-benzodiazepine receptors.

@article{Shrestha2012RhusPA,
  title={Rhus parviflora and its biflavonoid constituent, rhusflavone, induce sleep through the positive allosteric modulation of GABA(A)-benzodiazepine receptors.},
  author={Sabina Shrestha and J. Park and Dae-Young Lee and J Cho and Suengmok Cho and Hye-Jin Yang and Hye-Im Yong and Min-Seok Yoon and Dae-Seok Han and Nam-In Baek},
  journal={Journal of ethnopharmacology},
  year={2012},
  volume={142 1},
  pages={213-20}
}
ETHNOPHARMACOLOGICAL RELEVANCE Rhus parviflora is referred as 'Tintidikah' in traditional medicinal system of south Asia (Ayurveda). It is used in treatment of Vāta vikāra, a condition related to neurological complications as well as cure for stomach disorders. MATERIALS AND METHODS Dried and powdered fruits of R. parviflora were extracted with 80% aqueous methanol (RPME). The concentrated extract was successively partitioned with distilled water (DW), ethyl acetate (EtOAc), and n-butanol (n… CONTINUE READING