Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers
@article{Ham2012RhodiumcatalyzedRC, title={Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers}, author={Young Jin Ham and Han Yu and Nam Doo Kim and Jung-Mi Hah and Khalid B. Selim and Hwan Geun Choi and Taebo Sim}, journal={Tetrahedron}, year={2012}, volume={68}, pages={1918-1925} }
13 Citations
Cobalt-Catalyzed Asymmetric Hydroboration/Cyclization of 1,6-Enynes with Pinacolborane.
- ChemistryJournal of the American Chemical Society
- 2017
We report a cobalt-catalyzed asymmetric hydroboration/cyclization of 1,6-enynes with catalysts generated from Co(acac)2 and chiral bisphosphine ligands and activated in situ by reaction with…
Synthesis and Rh-catalyzed reductive cyclization of 1,6-enynes and 1,6-diynes containing alkynylboronate termini
- Chemistry
- 2020
Metal-catalyzed enyne cycloisomerization in natural product total synthesis
- Chemistry
- 2017
Since the seminal work of B. M. Trost et al. in 1985, metal catalyzed enyne cycloisomerization has become a fast growing and fascinating field. Due to its diversified chemistry and ability to…
Computational ligand design in enantio- and diastereoselective ynamide [5+2] cycloisomerization
- ChemistryNature communications
- 2016
This work shows how a combined theoretical and experimental approach enables the design of a highly reactive rhodium catalyst for the stereoselective cycloisomerization of ynamide-vinylcyclopropanes to [5.3.0]-azabicycles.
Development and mechanistic investigations into metal-catalysed cycloisomerisation of enynamides
- Chemistry
- 2017
This thesis reports the work on investigations into the mechanism of palladium-catalysed enynamide cycloisomerisations (with Pd(OAc)2 / bis(benzylidene)ethylenediamine (bbeda) catalyst system in…
Structure assignment of lucentamycin E and revision of the olefin geometries of the marine-derived lucentamycins.
- ChemistryJournal of natural products
- 2012
It is shown that the olefin geometries of the substituted proline functionalities must be revised to (2S,3R,E)-3-methyl-4-ethylideneproline, opposite of that previously reported.
Recent advances in rhodium-catalyzed asymmetric synthesis of heterocycles.
- Chemistry, BiologyOrganic & biomolecular chemistry
- 2017
This review focuses on the recent impressive progress and advances in the asymmetric synthesis of heterocycles under rhodium catalysis.
Total synthesis and structural revision of lucentamycin A.
- ChemistryThe Journal of organic chemistry
- 2012
The first total synthesis of lucentamycin A is reported, which confirms that the ethylidene substituent in Emp bears an E geometry, in contrast to the originally assigned Z configuration.
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The bis(imino)pyridine iron dinitrogen complex (((i)Pr)PDI)Fe(N(2))(2) catalyzes the hydrogen-mediated reductive cyclization of enynes and diynes with turnover frequencies comparable to those of…