Rhodium-catalyzed cycloaddition of 1,6-enynes with 2-bromophenylboronic acids: synthesis of a multi-substituted dihydronaphthalene scaffold.


A formal [2 + 2 + 2] cycloaddition of a 1,6-enyne with 2-bromophenylboronic acid has been realized to construct a multi-substituted dihydronaphthalene scaffold, in which the direct reductive elimination mechanism of aryl-Rh(iii)-C(sp(3)) species has been established to form an aryl-C(sp(3)) bond. 
DOI: 10.1039/b910532h

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