Rhodium-catalyzed asymmetric ring opening of oxabicyclic alkenes with organoboronic acids.


The first rhodium(I)-catalyzed asymmetric addition of organoboronic acids to oxabicyclic alkenes is reported. This asymmetric ring-opening (ARO) reaction can proceed in high yield under very mild conditions with electronically diverse organoboronic acids, in a highly diastereoselective and enantioselective manner. [structure: see text] 


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