Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation.

@article{Colby2010RhodiumcatalyzedCB,
  title={Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation.},
  author={D. A. Colby and R. G. Bergman and J. Ellman},
  journal={Chemical reviews},
  year={2010},
  volume={110 2},
  pages={
          624-55
        }
}
Once considered the 'holy grail' of organometallic chemistry, synthetically useful reactions employing C-H bond activation have increasingly been developed and applied to natural product and drug synthesis over the past decade. The ubiquity and relative low cost of hydrocarbons makes C-H bond functionalization an attractive alternative to classical C-C bond forming reactions such as cross-coupling, which require organohalides and organometallic reagents. In addition to providing an atom… Expand

Paper Mentions

Rhodium catalyzed chelation-assisted C-H bond functionalization reactions.
sp2 C-H bond activation in water and catalytic cross-coupling reactions.
Iron-Catalyzed C-H Bond Activation.
Bidentate, monoanionic auxiliary-directed functionalization of carbon-hydrogen bonds.
Amide-directed tandem C-C/C-N bond formation through C-H activation.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 51 REFERENCES
Metal-catalyzed cross-coupling reactions
Organometallics 2008;27:4758.(b) See also refs 89a and 70e-h
  • Colby et al. Page 36 Chem Rev. Author manuscript; available in PMC 2011 February 10. N IH PA Athor M anscript N IH PA Athor M anscript N IH PA Athor M anscript
  • 2011
1j, 40d,f,g, and 70a
  • J. Am. Chem. Soc
  • 2008
For examples of chelation-assisted arylation methods by Ru or Pd catalysis, see reference 1j as well as the following and leading references therein
  • Tetrahedron
  • 2008
For uncatalyzed and proton - catalyzed 1 , 2 - hydrogen shifts at imidazol - 2 - yl carbenes , see : ( a )
  • Organometallics
  • 2008
Handbook of C-H Transformations 2005,1,303
  • Bosnich, B. Acc. Chem. Res
  • 2008
Tetrahedron 2008,64,6073
  • For an example of a general cross-coupling method,
  • 2008
chelation-assisted arylation methods by Ru or Pd catalysis, see ref 1j as well as the following and leading references therein
  • Tetrahedron
  • 2008
2001:386.For leading references on the use of aldehydes in hydroacylation reactions
  • Eur J Org Chem 2007:1869
  • 2007
Dalton 2001:2437
  • Bercaw JE, Labinger JA. Nature 2002;417:507. [PubMed: 12037558] (c) Bergman RG. Nature 2007;446:391
  • 2007
...
1
2
3
4
5
...