Rhodiola Rosea L.- An Evaluation of Safety and Efficacy in the Context of a Neurological Disorder, Alzheimer Disease
@inproceedings{Ahmed2015RhodiolaRL,
title={Rhodiola Rosea L.- An Evaluation of Safety and Efficacy in the Context of a Neurological Disorder, Alzheimer Disease},
author={Fida Ahmed},
year={2015}
}.................................................................................................................................. ii RÉSUMÉ ...................................................................................................................................... iii ACKNOWLEDGEMENTS ........................................................................................................ iv TABLE OF CONTENTS…
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2 Citations
Nunavik Rhodiola rosea Attenuates Expression of Fear-Potentiated Startle
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Oral administration of R. rosea ethanolic extract significantly attenuated fear-potentiated startle, but did not produce any effects on stress-induced secretion of corticosterone.
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Significant improvement in GAD symptoms was found with R. rosea, with a reduction in HARS scores similar to that found in clinical trials, and these preliminary findings warrant further exploration of treatment with the herbal supplement in clinical samples.
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Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease and the level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with rosin and salidroside.
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The methanol extract of the underground part of Rhodiola rosea was found to show inhibitory activity against Staphylococcus aureus and Cytotoxicity studies of 1 and 2 displayed activity against the prostate cancer cell line with IC50 values of 50 µG/mL and 80 µg/mL, respectively.