Rhodanese as a thioredoxin oxidase.

@article{Nandi2000RhodaneseAA,
  title={Rhodanese as a thioredoxin oxidase.},
  author={D. L. Nandi and Paul M. Horowitz and John W. Westley},
  journal={The international journal of biochemistry & cell biology},
  year={2000},
  volume={32 4},
  pages={465-73}
}
A major catalytic difference between the two most common isoforms of bovine liver mitochondrial rhodanese (thiosulfate: cyanide sulfurtransferase, EC 2.8.1.1) has been observed. Both isoforms were shown to be capable of using reduced thioredoxin as a sulfur-acceptor substrate. However, only the less negative form in common with the recombinant mammalian rhodanese expressed in E. coli, can also catalyze the direct oxidation of reduced thioredoxin evidently by reactive oxygen species. These… CONTINUE READING