Rho localization in cells and tissues.

  title={Rho localization in cells and tissues.},
  author={Shigenobu Yonemura and Kazuyo Hirao-Minakuchi and Yukako Nishimura},
  journal={Experimental cell research},
  volume={295 2},
Rho family small GTPases regulate cytoskeletal organization. Although their spatiotemporal activities appear to be important for cellular morphogenesis, there has been little characterization of the localization of Rho family GTPases in cells and tissues. Here we show precise localization of Rho subfamily proteins in mammalian cultured cells and tissues through evaluation of anti-Rho antibodies and fixation protocols. Although Rho is not a structural protein but functions as a switching… CONTINUE READING
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