Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.

@article{Sander1999RholikeGT,
  title={Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.},
  author={Eva E. Sander and John G. Collard},
  journal={European journal of cancer},
  year={1999},
  volume={35 9},
  pages={1302-8}
}
The family members of small Rho-like GTPases, RhoA, Rac1 and Cdc42Hs, are regulators of diverse cellular signalling pathways, including cytoskeletal organisation, transcription and cell-cycle progression. Recent research has given insight into the complex regulation of cell-cell adhesion and migratory responses of epithelial cells. The Rho-like GTPases RhoA, Rac1 and Cdc42Hs as major determinants of cytoskeletal organisation have been identified as key regulators of epithelial architecture, as… CONTINUE READING

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