Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.

  title={Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.},
  author={Eva E. Sander and John G. Collard},
  journal={European journal of cancer},
  volume={35 9},
The family members of small Rho-like GTPases, RhoA, Rac1 and Cdc42Hs, are regulators of diverse cellular signalling pathways, including cytoskeletal organisation, transcription and cell-cycle progression. Recent research has given insight into the complex regulation of cell-cell adhesion and migratory responses of epithelial cells. The Rho-like GTPases RhoA, Rac1 and Cdc42Hs as major determinants of cytoskeletal organisation have been identified as key regulators of epithelial architecture, as… CONTINUE READING

From This Paper

Topics from this paper.
26 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…