Rho and RNA: models for recognition and response.

  title={Rho and RNA: models for recognition and response.},
  author={T. Platt},
  journal={Molecular microbiology},
  volume={11 6},
  • T. Platt
  • Published 1994 in Molecular microbiology
Escherichia coli Rho factor is required for termination of transcription at certain sites by RNA polymerase. Binding to unstructured cytosine-containing RNA target sites, subsequent RNA-dependent ATP hydrolysis, and an RNA-DNA helicase activity that presumably facilitates termination, are considered essential for Rho function. Yet the RNA recognition elements have remained elusive, the parameters relating RNA binding to ATPase activation have been obscure, and the mechanistic steps that… CONTINUE READING