Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.

@article{Chircop2014RhoGA,
  title={Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.},
  author={Megan Chircop},
  journal={Small GTPases},
  year={2014},
  volume={5}
}
Rho GTPases regulate a diverse range of cellular functions primarily through their ability to modulate microtubule dynamics and the actin-myosin cytoskeleton. Both of these cytoskeletal structures are crucial for a mitotic cell division. Specifically, their assembly and disassembly is tightly regulated in a temporal manner to ensure that each mitotic stage occurs in the correct sequential order and not prematurely until the previous stage is completed. Thus, it is not surprising that the Rho… CONTINUE READING
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