RhlR expression in Pseudomonas aeruginosa is modulated by the Pseudomonas quinolone signal via PhoB-dependent and -independent pathways.

@article{Jensen2006RhlREI,
  title={RhlR expression in Pseudomonas aeruginosa is modulated by the Pseudomonas quinolone signal via PhoB-dependent and -independent pathways.},
  author={Vanessa K. Jensen and Dagmar L{\"o}ns and Caroline Zaoui and Florian Bredenbruch and Andree Meissner and Guido Dieterich and Richard M{\"u}nch and S. H{\"a}u\ssler},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 24},
  pages={8601-6}
}
The expression of virulence determinants in Pseudomonas aeruginosa is coordinately regulated in response to both the social environment--commonly referred to as quorum sensing--and to environmental cues. In this study we have dissected the various independent regulation levels for pyocyanin production, which is influenced by the homoserine lactone- and Pseudomonas quinolone signal (PQS)-mediated quorum-sensing systems as well as by iron and phosphate availability. We demonstrate that the… CONTINUE READING

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