Rhizoxin resistant mutants with an altered β-tubulin gene in Aspergillus nidulans

Abstract

Rhizoxin and ansamitocin P-3 (a maytansinoid compound), potent inhibitors of mammalian brain tubulin assembly, inhibit growth of a variety of fungi including Aspergillus nidulans. Mutants of A. nidulans, benA10 which is a benomyl resistant β-tubulin gene mutant and tubAl which is a benomyl supersensitive a-tubulin gene mutant, were both sensitive to… (More)
DOI: 10.1007/BF00260855

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@article{Takahashi1989RhizoxinRM, title={Rhizoxin resistant mutants with an altered β-tubulin gene in Aspergillus nidulans}, author={Masaaki Takahashi and Msayoshi Kobayashi and Shigeo Iwasaki}, journal={Molecular and General Genetics MGG}, year={1989}, volume={220}, pages={53-59} }