Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1β.

@article{Terajima1997RhinovirusIO,
  title={Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1β.},
  author={Masanori Terajima and Mutsuo Yamaya and Kiyohisa Sekizawa and Shoji Okinaga and Tomoko Suzuki and Norihiro Yamada and Katsutoshi Nakayama and Takashi Ohrui and Takeko Oshima and Yoshio Numazaki and Hidetada Sasaki},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={1997},
  volume={273 4},
  pages={L749-L759}
}
Exacerbations of asthma are often associated with respiratory infection caused by rhinoviruses. To study the effects of rhinovirus infection on respiratory epithelium, a primary target for respiratory viruses, human rhinovirus (HRV)-2 and HRV-14 were infected to primary cultures of human tracheal epithelial cells. Viral infection was confirmed by showing that viral titers of supernatants and lysates from infected cells increased with time and by polymerase chain reaction. HRV-2 and HRV-14… CONTINUE READING