Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release.

@article{Bossios2008RhinovirusIA,
  title={Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release.},
  author={Apostolos Bossios and Dimitrios Gourgiotis and Chrysanthi L Skevaki and Photini Saxoni-Papageorgiou and Jan L{\"o}tvall and Stelios Psarras and Themistoclis Karpathios and A G Constandopoulos and Sebastian L Johnston and Nikolaos G. Papadopoulos},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2008},
  volume={38 10},
  pages={1615-26}
}
BACKGROUND Human rhinoviruses (HRVs) and house dust mites (HDMs) are among the most common environmental factors able to induce airway inflammation in asthma. Although epidemiological studies suggest that they also synergize in inducing asthma exacerbations, there is no experimental evidence to support this, nor any information on the possible mechanisms involved. OBJECTIVE To investigate their interaction on the induction of airway epithelial inflammatory responses in vitro. METHODS BEAS… CONTINUE READING

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