Rheumatoid factor, cryoglobulinemia, anti-DNA, and renal disease in patients with systemic lupus erythematosus.

@article{Howard1991RheumatoidFC,
  title={Rheumatoid factor, cryoglobulinemia, anti-DNA, and renal disease in patients with systemic lupus erythematosus.},
  author={T W Howard and M J Iannini and J J Burge and John S. Davis},
  journal={The Journal of rheumatology},
  year={1991},
  volume={18 6},
  pages={826-30}
}
We retrospectively analyzed the relationship between rheumatoid factor (RF) and renal disease in 102 patients with systemic lupus erythematosus (SLE). We found a significant negative association between detectable RF at any time in a patient's course and clinically significant renal diseases. Multivariate analysis indicates that RF and cryoglobulins, operating independently, have a significant and opposite association with the development of renal disease in patients with SLE. These… CONTINUE READING