Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles.

@article{Lebre2008RheumatoidAS,
  title={Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles.},
  author={Maria Cristina Lebre and Sarah L. Jongbloed and Sander W. Tas and Tom J. M. Smeets and Iain B. Mcinnes and Paul Peter Tak},
  journal={The American journal of pathology},
  year={2008},
  volume={172 4},
  pages={940-50}
}
Dendritic cells (DCs) have been proposed to play a pivotal role in the initiation and perpetuation of rheumatoid arthritis (RA) by presentation of arthritogenic antigens to T cells. We investigated the in vivo characteristics of two major DC subsets, myeloid DCs (mDCs) and plasmacytoid DCs (pDCs), in RA synovial tissue (ST) by measuring their frequency… CONTINUE READING