Rheumatoid arthritis complicated by pachy- and leptomeningeal rheumatoid nodule-like granulomas and systemic vasculitis.

@article{Kamio1996RheumatoidAC,
  title={Rheumatoid arthritis complicated by pachy- and leptomeningeal rheumatoid nodule-like granulomas and systemic vasculitis.},
  author={Naohiko Kamio and Shigeru Kuramochi and Rong Juan Wang and Shinichi Hirose and Yoshisuke Hosoda},
  journal={Pathology international},
  year={1996},
  volume={46 7},
  pages={526-30}
}
Rheumatoid nodule is a frequent and characteristic extra-articular manifestation of rheumatoid arthritis (RA). Its involvement of central nervous system is a rare occurrence with only a few reported cases. A 78-year-old man with severe arthritis showing the formation of rheumatoid nodule-like granulomas in the dura and subarachnoid space along with the spleen is presented. The characteristic morphological finding of the granulomas was the presence of neutrophils and the absence of definite… CONTINUE READING