Rhabdomyosarcomas in adults and children: an update.

  title={Rhabdomyosarcomas in adults and children: an update.},
  author={David M. Parham and Dale A Ellison},
  journal={Archives of pathology & laboratory medicine},
  volume={130 10},
CONTEXT Rhabdomyosarcomas comprise a relatively common diagnostic entity among childhood cancers and a relatively rare one among adult tumors. They may possess a variety of histologies that generally differ among age groups. These lesions appear to be separate biologic entities as well as morphologic categories, with embryonal tumors having genetic lesions related to loss of heterozygosity and aberrant parental imprinting, alveolar tumors containing genetic fusions between PAX and forkhead… CONTINUE READING
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