Rhabdomyosarcoma: an overview.

  title={Rhabdomyosarcoma: an overview.},
  author={Ramzi Dagher and Lee Helman},
  journal={The oncologist},
  volume={4 1},
Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin thought to arise from cells committed to a skeletal muscle lineage. With approximately 250 cases diagnosed yearly in the United States, it is the third most common extracranial solid tumor of childhood after Wilms' tumor and neuroblastoma. Important epidemiologic, biologic, and therapeutic differences have been elucidated within the RMS family. Common sites of primary disease include the head and neck region, genitourinary tract… CONTINUE READING