Rhabdomyolysis: A review

@article{Warren2002RhabdomyolysisAR,
  title={Rhabdomyolysis: A review},
  author={Jason D. Warren and Peter Blumbergs and Philip Douglas Thompson},
  journal={Muscle \& Nerve},
  year={2002},
  volume={25}
}
Rhabdomyolysis, a syndrome of skeletal muscle breakdown with leakage of muscle contents, is frequently accompanied by myoglobinuria, and if sufficiently severe, acute renal failure with potentially life‐threatening metabolic derangements may ensue. A diverse spectrum of inherited and acquired disorders affecting muscle membranes, membrane ion channels, and muscle energy supply causes rhabdomyolysis. Common final pathophysiological mechanisms among these causes of rhabdomyolysis include an… 
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TLDR
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TLDR
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TLDR
The mortality rate ranges from 10% to up to 50% with severe AKI, so high index of suspicion and screening should be in care plan of seriously ill patients at risk for RML.
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